Preventing effect of L-type calcium channel blockade on electrophysiological alterations in dentate gyrus granule cells induced by entorhinal amyloid pathology.

Preventing effect of L-type calcium channel blockade on electrophysiological alterations in dentate gyrus granule cells induced by entorhinal amyloid pathology.

The entorhinal cortex (EC) is one of the earliest affected brain regions in Alzheimer's disease (AD). EC-amyloid pathology induces synaptic failure in the dentate gyrus (DG) with resultant behavioral impairment, but there is little known about its impact on neuronal properties in the DG. It is...

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Bibliographic Details
Main Authors: Hamid Gholami Pourbadie, Nima Naderi, Nasrin Mehranfard, Mahyar Janahmadi, Fariba Khodagholi, Fereshteh Motamedi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4331091?pdf=render

Internet

http://europepmc.org/articles/PMC4331091?pdf=render

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