A Randomized Trial of Topical Fibrinogen-Depleted Human Platelet Lysate Treatment of Dry Eye Secondary to Chronic Graft-versus-Host Disease

Purpose: The purpose of the study was to evaluate, as a pilot trial, safety and tolerability of CAM-101 10% and 30% topical ophthalmic fibrinogen-depleted human platelet lysate (FD hPL) solution in patients with dry eye disease (DED) secondary to graft-versus-host disease (GvHD) after 6 weeks of tre...

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Main Authors: Alan Sugar, MD, Munira Hussain, MS, Winston Chamberlain, MD, PhD, Reza Dana, MD, David Patrick Kelly, MD, Christopher Ta, MD, John Irvine, MD, Melissa Daluvoy, MD, Victor Perez, MD, Joshua Olson, MD, Vishal Jhanji, MD, Terence A. Walts, MBA, Robert Doyle Stulting, MD, PhD, Edmund K. Waller, MD, PhD, Neera Jagirdar, MD, MPH, Shahzad Mian, MD, Roni Shtein, MD, H. Kaz Soong, MD, Munira Hussain, Afshan Nanji, MD, MPH, John Clements, MD, Jennifer Maykovski, Paula Cisternas Labadzinzki, Jia Jin, MD, Joseph Ciolino, MD, John Caccaviello, D. Patrick Kelly, MD, Roya Habibi, OD, Charles Yu, MD, Charles Lin, MD, Kristin Hirabayashi, MD, Gabriel Valerio, MD, Supriya Kawale, Mariana Nunez, Olivia Lee, MD, Matthew Chu, Elmer Balajonda, Terry Hawks, Amanda Maltry, MD, Joshua Hou, MD, Wendy Elasky, Rose Carla Aubourg, R. Doyle Stulting, MD, PhD, Edmund Waller, MD, PhD, Neera Jagirdar, MD, Terence Walts
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Ophthalmology Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666914522000653