LncRNA MEG3 Protects Chondrocytes From IL-1β-Induced Inflammation via Regulating miR-9-5p/KLF4 Axis

LncRNA MEG3 Protects Chondrocytes From IL-1β-Induced Inflammation via Regulating miR-9-5p/KLF4 Axis

BackgroundOsteoarthritis (OA) is a chronic degenerative disease of the joints characterized by articular cartilage damage, subchondral bone remodeling, osteophyte formation, and inflammatory changes. This work aims to investigate the protective role of long non-coding RNA (lncRNA) maternally express...

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Bibliographic Details
Main Authors: Yijiang Huang, Daosen Chen, Zijian Yan, Jingdi Zhan, Xinghe Xue, Xiaoyun Pan, Huachen Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
inflammation
apoptosis
proliferation
OA
KLF4
miR-9-5p
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.617654/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.617654/full

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