Mutation analysis of the TUBB8 gene in primary infertile women with oocyte maturation arrest

Mutation analysis of the TUBB8 gene in primary infertile women with oocyte maturation arrest

Abstract Background Oocyte maturation arrest at metaphase I leads to fertilization failure in humans. In early embryos, the tubulin beta 8 class VIII (TUBB8) encodes a β-tubulin isotype and aids in the assembling of the human oocyte spindle. Mutations in the TUBB8 potentially interfere with human oo...

Full description

Bibliographic Details
Main Authors: Zhongyuan Yao, Jun Zeng, Huimin Zhu, Jing Zhao, Xiaoxia Wang, Qiuping Xia, Yanping Li, Lingqian Wu
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Ovarian Research
Subjects:
Oocyte MI arrest
Female infertility
TUBB8
Mutation
Online Access:https://doi.org/10.1186/s13048-022-00971-9

Internet

https://doi.org/10.1186/s13048-022-00971-9

Similar Items