Novel regulator of acylated ghrelin, CF801, reduces weight gain, rebound feeding after a fast, and adiposity in mice

Novel regulator of acylated ghrelin, CF801, reduces weight gain, rebound feeding after a fast, and adiposity in mice

Ghrelin is a 28 amino-acid hormonal peptide that is intimately related to the regulation of food intake and body weight. Once secreted, ghrelin binds to the growth hormone secretagogue receptor-1a (GHSR-1a), the only known receptor for ghrelin and is capable of activating a number of signaling casca...

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Bibliographic Details
Main Authors: Martin K Wellman, Zachary Robert Patterson, Harry eMackay, Joseph E Darling, Bharath K Mani, Jeffrey eZigman, James L Hougland, Alfonso eAbizaid
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Endocrinology
Subjects:
Adiposity
Appetite
Ghrelin
Weight Loss
Energy Expenditure
ghrelin-O-acyltransferase
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00144/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00144/full

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