Simple approach to thieno[3,2-d]pyrimidines as new scaffolds of antimicrobial activities

6ʹ-(4-Chlorophenyl)-spiro[cyclohexane-1,2ʹ-thieno[3,2-d][1,3] oxazin]-4ʹ(1ʹH)-one (1) was synthesized and used as a starting material for the synthesis of a novel series of spiro compounds having biologically active sulfonamide 2a-e and 3ʹ-(4-acetylphenyl)-6ʹ- (4-chlorophenyl)-1ʹH-spiro[cyclohexane-...

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Bibliographic Details
Main Authors: Hafez Hend N., El-Gazzar Abdel-Rhman B. A., Zaki Magdi E. A.
Format: Article
Language:English
Published: Sciendo 2016-09-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.1515/acph-2016-0029