Antigenic molecular mimicry in viral-mediated protection from cancer: the HIV case

Antigenic molecular mimicry in viral-mediated protection from cancer: the HIV case

Abstract Background People living with HIV/AIDS (PLWHA) show a reduced incidence for three cancer types, namely breast, prostate and colon cancers. In the present study, we assessed whether a molecular mimicry between HIV epitopes and tumor associated antigens and, consequently, a T cell cross-react...

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Bibliographic Details
Main Authors: Carmen Manolio, Concetta Ragone, Beatrice Cavalluzzo, Angela Mauriello, Maria Lina Tornesello, Franco M. Buonaguro, Angelo Salomone Megna, Giovanna D’Alessio, Roberta Penta, Maria Tagliamonte, Luigi Buonaguro
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Translational Medicine
Subjects:
Tumor-associated antigens
Viral antigens
Molecular mimicry
Cross-reactive T cells
HIV-1
Colon cancer
Online Access:https://doi.org/10.1186/s12967-022-03681-4

Internet

https://doi.org/10.1186/s12967-022-03681-4

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