Reward processing in schizophrenia and its relation to Mu opioid receptor availability and negative symptoms: A [11C]-carfentanil PET and fMRI study

Reward processing in schizophrenia and its relation to Mu opioid receptor availability and negative symptoms: A [11C]-carfentanil PET and fMRI study

Background: Reward processing deficits are a core feature of schizophrenia and are thought to underlie negative symptoms. Pre-clinical evidence suggests that opioid neurotransmission is linked to reward processing. However, the contribution of Mu Opioid Receptor (MOR) signalling to the reward proces...

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Bibliographic Details
Main Authors: Ekaterina Shatalina, Abhishekh H. Ashok, Matthew B. Wall, Matthew M. Nour, Jim Myers, Tiago Reis Marques, Eugenii A. Rabiner, Oliver D. Howes
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Mu opioid receptor
Reward
Functional MRI
PET
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223001729

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http://www.sciencedirect.com/science/article/pii/S2213158223001729

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