Control of pre-replicative complex during the division cycle in Chlamydomonas reinhardtii.

DNA replication is fundamental to all living organisms. In yeast and animals, it is triggered by an assembly of pre-replicative complex including ORC, CDC6 and MCMs. Cyclin Dependent Kinase (CDK) regulates both assembly and firing of the pre-replicative complex. We tested temperature-sensitive mutan...

Full description

Bibliographic Details
Main Authors: Amy E Ikui, Noriko Ueki, Kresti Pecani, Frederick R Cross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009471