Poly(N-isopropylacrylamide-co-N-vinylpyrrolidone) thermoresponsive microspheres: The low drug loading ensures the pulsatile release mechanism

Poly(N-isopropylacrylamide-co-N-vinylpyrrolidone) (poly(NIPAAm-co-NVP)) with a co-monomer molar ratio in copolymer of 91.5/8.5 (NIPAAm/NVP) was synthesized as an interesting thermosensitive material possessing a sharp phase transition at 36 °C under simulated physiological conditions. The effect of...

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Bibliographic Details
Main Authors: G. Fundueanu, M. Constantin, S. Bucatariu, P. Ascenzi
Format: Article
Language:English
Published: Budapest University of Technology 2020-01-01
Series:eXPRESS Polymer Letters
Subjects:
Online Access:http://www.expresspolymlett.com/letolt.php?file=EPL-0010125&mi=cd