OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis
Backgrounds The role of O-GlcNAc transferase (OGT)-induced O-linked N-acetylglucosaminylation (O-GlcNAcylation) has been reported in multiple human diseases. However, its specific functions in osteoarthritis (OA) progression remain undetermined.Objective This study focused on the target proteins of...
Autores principales: | , , , , , , |
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Formato: | Artículo |
Lenguaje: | English |
Publicado: |
Taylor & Francis Group
2024-12-01
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Colección: | Autoimmunity |
Materias: | |
Acceso en línea: | https://www.tandfonline.com/doi/10.1080/08916934.2024.2319202 |