Cerebral perfusion and metabolism with mild hypercapnia vs. normocapnia in a porcine post cardiac arrest model with and without targeted temperature management

Cerebral perfusion and metabolism with mild hypercapnia vs. normocapnia in a porcine post cardiac arrest model with and without targeted temperature management

Aim: To determine whether targeting mild hypercapnia (PaCO2 7 kPa) would yield improved cerebral blood flow and metabolism compared to normocapnia (PaCO2 5 kPa) with and without targeted temperature management to 33 °C (TTM33) in a porcine post-cardiac arrest model. Methods: 39 pigs were resuscitate...

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Bibliographic Details
Main Authors: Hilde Karlsen, Runar J Strand-Amundsen, Christiane Skåre, Morten Eriksen, Vidar M Skulberg, Kjetil Sunde, Tor Inge Tønnessen, Theresa M Olasveengen
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Resuscitation Plus
Subjects:
Resuscitation
post-ROSC
Cardiac arrest
Ventilation
Hypercapnia
Experimental study
Online Access:http://www.sciencedirect.com/science/article/pii/S2666520424000559

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http://www.sciencedirect.com/science/article/pii/S2666520424000559

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