NAP1L1 regulates BIRC2 ubiquitination modification via E3 ubiquitin ligase UBR4 and hence determines hepatocellular carcinoma progression

NAP1L1 regulates BIRC2 ubiquitination modification via E3 ubiquitin ligase UBR4 and hence determines hepatocellular carcinoma progression

Abstract We have previously shown that nucleosome assembly protein 1-like 1 (NAP1L1) plays an important role in the abnormal proliferation of hepatocellular carcinoma (HCC) cells. However, the effects of NAP1L1 on the malignant behaviour of HCC cells, including cell migration, invasion and apoptosis...

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Bibliographic Details
Main Authors: Shi-Long Zhang, Shen-Jie Zhang, Lian Li, Ye-Wei Zhang, Zhi Wang, Long Wang, Jie-Yu Lu, Teng-Xiang Chen, Shi Zuo
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01927-2

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https://doi.org/10.1038/s41420-024-01927-2

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