Role of CBL Mutations in Cancer and Non-Malignant Phenotype

Role of CBL Mutations in Cancer and Non-Malignant Phenotype

CBL plays a key role in different cell pathways, mainly related to cancer onset and progression, hematopoietic development and T cell receptor regulation. Somatic <i>CBL</i> mutations have been reported in a variety of malignancies, ranging from acute myeloid leukemia to lung cancer. Gro...

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Bibliographic Details
Main Authors: Davide Leardini, Daria Messelodi, Edoardo Muratore, Francesco Baccelli, Salvatore N. Bertuccio, Laura Anselmi, Andrea Pession, Riccardo Masetti
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
CBL
CBL syndrome
cancer predisposition
JMML
pediatric oncology
Online Access:https://www.mdpi.com/2072-6694/14/3/839

Internet

https://www.mdpi.com/2072-6694/14/3/839

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