iPSC-Derived Macrophages: The Differentiation Protocol Affects Cell Immune Characteristics and Differentiation Trajectories

iPSC-Derived Macrophages: The Differentiation Protocol Affects Cell Immune Characteristics and Differentiation Trajectories

The generation of human macrophages from induced pluripotent stem cells (iMacs) is a rapidly developing approach used to create disease models, screen drugs, study macrophage–pathogen interactions and develop macrophage-based cell therapy. To generate iMacs, different types of protocols have been su...

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Bibliographic Details
Main Authors: Anna Klepikova, Tatiana Nenasheva, Olga Sheveleva, Elena Protasova, Daniil Antonov, Anastasiia Gainullina, Evgeniia Chikina, Olga Sakovnich, Tatiana Gerasimova, Irina Nikitina, Dmitry Shevalie, Irina Lyadova
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
induced pluripotent stem cells
macrophages derived from induced pluripotent stem cells
macrophage differentiation
inflammatory response
antigen presentation
lipid homeostasis
Online Access:https://www.mdpi.com/1422-0067/23/24/16087

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https://www.mdpi.com/1422-0067/23/24/16087

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