Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental PancreatitisSummary

Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental PancreatitisSummary

Background: Autophagosome, the central organelle in autophagy process, can assemble via canonical pathway mediated by LC3-II, the lipidated form of autophagy-related protein LC3/ATG8, or noncanonical pathway mediated by the small GTPase Rab9. Canonical autophagy is essential for exocrine pancreas ho...

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Bibliographic Details
Main Authors: Olga A. Mareninova, Dustin L. Dillon, Carli J.M. Wightman, Iskandar Yakubov, Toshimasa Takahashi, Herbert Y. Gaisano, Keith Munson, Masaki Ohmuraya, David Dawson, Ilya Gukovsky, Anna S. Gukovskaya
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Autophagosome
Alternative Autophagy
Rab GTPase
RabGDI
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21002071

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X21002071

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