sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity

Uncontrolled inflammatory responses play a critical role in coronavirus disease (COVID-19). In this context, because the triggering-receptor expressed on myeloid cells-1 (TREM-1) is considered an intrinsic amplifier of inflammatory signals, this study investigated the role of soluble TREM-1 (sTREM-1...

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Main Authors: Pedro V. da Silva-Neto, Jonatan C. S. de Carvalho, Vinícius E. Pimentel, Malena M. Pérez, Diana M. Toro, Thais F. C. Fraga-Silva, Carlos A. Fuzo, Camilla N. S. Oliveira, Lilian C. Rodrigues, Jamille G. M. Argolo, Ingryd Carmona-Garcia, Nicola T. Neto, Camila O. S. Souza, Talita M. Fernandes, Victor A. F. Bastos, Augusto M. Degiovani, Leticia F. Constant, Fátima M. Ostini, Marley R. Feitosa, Rogerio S. Parra, Fernando C. Vilar, Gilberto G. Gaspar, José J. R. da Rocha, Omar Feres, Fabiani G. Frantz, Raquel F. Gerlach, Sandra R. Maruyama, Elisa M. S. Russo, Angelina L. Viana, Ana P. M. Fernandes, Isabel K. F. M. Santos, Vânia L. D. Bonato, Antonio L. Boechat, Adriana Malheiro, Ruxana T. Sadikot, Marcelo Dias-Baruffi, Cristina R. B. Cardoso, Lúcia H. Faccioli, Carlos A. Sorgi, on behalf of the IMUNOCOVID Study Group
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/12/2521