LOX-1 attenuates high glucose-induced autophagy via AMPK/HNF4α signaling in HLSECs

Type 2 diabetes mellitus (T2DM) combined with nonalcoholic fatty liver disease (NAFLD) is a common cause of death. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is involved in the regulation of autophagy and associated with a variety of diseases, such as atherosclerosis, diabetes,...

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Bibliographic Details
Main Authors: Qidang Duan, Huiling Si, Limin Tian, Na Zhang, Jumei Qiu, Jing Yu, Jing Liu, Qi Zhang
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022036738