Aneuploid serves as a prognostic marker and favors immunosuppressive microenvironment in ovarian cancer

Aneuploid serves as a prognostic marker and favors immunosuppressive microenvironment in ovarian cancer

Abstract Ovarian cancer is the most lethal gynecologic neoplasm, and most patients experience recurrence and chemoresistance. Even the promising immunotherapy showed limited efficacy in ovarian cancer, probably due to the immunosuppressive microenvironment. However, the behind mechanisms of the immu...

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Bibliographic Details
Main Authors: Ming Du, Qingqing Cai, Jiaan Sun, Mingxing Zhang, Shuo Zhang, Xiaoxia Liu, Mengyu Zhang, Xiaoyan Zhang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Aneuploid
Chromosome alteration
Immune microenvironment
Antigen presentation
Online Access:https://doi.org/10.1186/s13048-024-01356-w

Internet

https://doi.org/10.1186/s13048-024-01356-w

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