Anticoagulation intensity of rivaroxaban for stroke patients at a special low dosage in Japan.

In Japan, low-dose rivaroxaban [15 mg QD/10 mg QD for creatinine clearance of 30-49 mL/min] was approved for clinical use in NVAF patients partly because of its unique pharmacokinetics in Japanese subjects. The aim of the study was to determine the anticoagulation intensity of rivaroxaban and its de...

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Bibliographic Details
Main Authors: Takuya Okata, Kazunori Toyoda, Akira Okamoto, Toshiyuki Miyata, Kazuyuki Nagatsuka, Kazuo Minematsu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4257912?pdf=render