Auxin-inducible degron system: an efficient protein degradation tool to study protein function

Targeted protein degradation, with its rapid protein depletion kinetics, allows the measurement of acute changes in the cell. The auxin-inducible degron (AID) system, rapidly degrades AID-tagged proteins only in the presence of auxin. The AID system being inducible makes the study of essential genes...

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Bibliographic Details
Main Authors: Kundurthi Phanindhar, Rakesh K Mishra
Format: Article
Language:English
Published: Taylor & Francis Group 2023-04-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/btn-2022-0108