Natural Killer Cells Prevent the Formation of Teratomas Derived From Human Induced Pluripotent Stem Cells

Natural Killer Cells Prevent the Formation of Teratomas Derived From Human Induced Pluripotent Stem Cells

The safe utilization of induced pluripotent stem cell (iPSC) derivatives in clinical use is attributed to the complete elimination of the risk of forming teratomas after transplantation. The extent by which such a risk exists in immune-competent hosts is mostly unknown. Here, using humanized mice re...

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Bibliographic Details
Main Authors: Basma Benabdallah, Cynthia Désaulniers-Langevin, Chloé Colas, Yuanyi Li, Guy Rousseau, Jean V. Guimond, Elie Haddad, Christian Beauséjour
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
induced pluripotent stem cell
humanized mice
adoptive transfer
NK cells
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02580/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02580/full

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