New insight into a simple high-yielding method for the production of fully folded and functional recombinant human CCL5

Abstract Chemokines are proteins important for a range of biological processes from cell-directed migration (chemotaxis) to cell activation and differentiation. Chemokine C-C ligand 5 (CCL5) is an important pro-inflammatory chemokine attracting immune cells towards inflammatory sites through interac...

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Bibliographic Details
Main Authors: Afzaal Tufail, Saeed Akkad, Amanda R. Noble, Martin A. Fascione, Nathalie Signoret
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-75327-y