Structural Basis of the Diversity of Adrenergic Receptors

Structural Basis of the Diversity of Adrenergic Receptors

Summary: Adrenergic receptors are highly homologous while at the same time display a wide diversity of ligand and G-protein binding, and understanding this diversity is key for designing selective or biased drugs for them. Here, we determine two crystal structures of the α2A adrenergic receptor (α2A...

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Bibliographic Details
Main Authors: Lu Qu, Qingtong Zhou, Yueming Xu, Yu Guo, Xiaoyu Chen, Deqiang Yao, Gye Won Han, Zhi-Jie Liu, Raymond C. Stevens, Guisheng Zhong, Dong Wu, Suwen Zhao
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471931410X

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http://www.sciencedirect.com/science/article/pii/S221112471931410X

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