Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure

Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure

Robo2 is the cell surface receptor for the repulsive guidance cue Slit and is involved in axon guidance and neuronal migration. Nephrin is a podocyte slit-diaphragm protein that functions in the kidney glomerular filtration barrier. Here, we report that Robo2 is expressed at the basal surface of mou...

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Bibliographic Details
Main Authors: Xueping Fan, Qinggang Li, Anna Pisarek-Horowitz, Hila Milo Rasouly, Xiangling Wang, Ramon G. Bonegio, Hang Wang, Margaret McLaughlin, Steve Mangos, Raghu Kalluri, Lawrence B. Holzman, Iain A. Drummond, Dennis Brown, David J. Salant, Weining Lu
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712001623

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http://www.sciencedirect.com/science/article/pii/S2211124712001623

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