An Automated Strategy for Unbiased Morphometric Analyses and Classifications of Growth Cones In Vitro.

During neural circuit development, attractive or repulsive guidance cue molecules direct growth cones (GCs) to their targets by eliciting cytoskeletal remodeling, which is reflected in their morphology. The experimental power of in vitro neuronal cultures to assay this process and its molecular mech...

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Bibliographic Details
Main Authors: Daryan Chitsaz, Daniel Morales, Chris Law, Artur Kania
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4619750?pdf=render