Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits

Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits

Background: Causality between plasma triglyceride (TG) levels and atherosclerotic cardiovascular disease (ASCVD) risk remains controversial despite more than four decades of study and two recent landmark trials, STRENGTH, and REDUCE-IT. Further unclear is the association between TG levels and non-at...

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Bibliographic Details
Main Authors: Joshua K Park, Shantanu Bafna, Iain S Forrest, Áine Duffy, Carla Marquez-Luna, Ben O Petrazzini, Ha My Vy, Daniel M Jordan, Marie Verbanck, Jagat Narula, Robert S Rosenson, Ghislain Rocheleau, Ron Do
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
Mendelian randomization
triglycerides
cardiovascular disease
UK Biobank
FinnGen
lipid metabolism
Online Access:https://elifesciences.org/articles/80560

Internet

https://elifesciences.org/articles/80560

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