Single-cell transcriptomics reveals cell type–specific immune regulation associated with anti-NMDA receptor encephalitis in humans

Single-cell transcriptomics reveals cell type–specific immune regulation associated with anti-NMDA receptor encephalitis in humans

IntroductionAnti-N-methyl-D-aspartate receptor encephalitis (anti-NMDARE) is a rare autoimmune disease, and the peripheral immune characteristics associated with anti-NMDARE antibodies remain unclear.MethodsHerein, we characterized peripheral blood mononuclear cells from patients with anti-NMDARE an...

Full description

Bibliographic Details
Main Authors: Yushu Jiang, Shuhua Dai, Linlin Jia, Lingzhi Qin, Milan Zhang, Huiqin Liu, Xiaojuan Wang, Rui Pang, Jiewen Zhang, Gongxin Peng, Wei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
anti-N-methyl-D-aspartate receptor encephalitis
peripheral blood mononuclear cell
single-cell RNA sequencing
B cells
plasma cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1075675/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1075675/full

Similar Items