Single-cell transcriptomics reveals cell type–specific immune regulation associated with anti-NMDA receptor encephalitis in humans

Single-cell transcriptomics reveals cell type–specific immune regulation associated with anti-NMDA receptor encephalitis in humans

IntroductionAnti-N-methyl-D-aspartate receptor encephalitis (anti-NMDARE) is a rare autoimmune disease, and the peripheral immune characteristics associated with anti-NMDARE antibodies remain unclear.MethodsHerein, we characterized peripheral blood mononuclear cells from patients with anti-NMDARE an...

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Bibliographic Details
Main Authors:	Yushu Jiang, Shuhua Dai, Linlin Jia, Lingzhi Qin, Milan Zhang, Huiqin Liu, Xiaojuan Wang, Rui Pang, Jiewen Zhang, Gongxin Peng, Wei Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Series:	Frontiers in Immunology
Subjects:	anti-N-methyl-D-aspartate receptor encephalitis peripheral blood mononuclear cell single-cell RNA sequencing B cells plasma cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1075675/full

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