Efficient protocol for the differentiation of kidney podocytes from induced pluripotent stem cells, involving the inhibition of mTOR

Efficient protocol for the differentiation of kidney podocytes from induced pluripotent stem cells, involving the inhibition of mTOR

Abstract The mechanistic/mammalian target of rapamycin (mTOR) is involved in a wide range of cellular processes. However, the role of mTOR in podocytes remains unclear. In this study, we aimed to clarify the role of mTOR in podocyte differentiation from human induced pluripotent stem cells (hiPSCs)...

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Main Authors: Masahiro Yasuda, Tadashi Kato, Mai Okano, Hiromi Yamashita, Yoshikazu Matsuoka, Yasumasa Shirouzu, Tatsuya Fujioka, Fumiyuki Hattori, Shoji Tsuji, Kazunari Kaneko, Hirofumi Hitomi
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47087-8

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https://doi.org/10.1038/s41598-023-47087-8

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