Genetic tagging of the adenosine A2A receptor reveals its heterogeneous expression in brain regions

Genetic tagging of the adenosine A2A receptor reveals its heterogeneous expression in brain regions

The adenosine A2A receptor (A2AR), a G protein-coupled receptor, is involved in numerous and varied physiological and pathological processes, including inflammation, immune responses, blood flow, and neurotransmission. Accordingly, it has become an important drug target for the treatment of neuropsy...

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Bibliographic Details
Main Authors: Muran Wang, Zewen Li, Yue Song, Qiuqin Sun, Lu Deng, Zhiqing Lin, Yang Zeng, Chunhong Qiu, Jingjing Lin, Hui Guo, Jiangfan Chen, Wei Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Neuroanatomy
Subjects:
adenosine A2A receptor (A2AR)
knock-in mice
CRISPR/Cas9
striatum
lateral septum (LS)
G protein-coupled receptor (GPCR)
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2022.978641/full

Internet

https://www.frontiersin.org/articles/10.3389/fnana.2022.978641/full

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