TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression

TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression

Abstract Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Virtually all women with DCIS are treated, despite evidence suggesting up to half would remain with stable, non-threatening, disease. Overtreatment thus presents a pressing issue in DCIS management. To un...

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Bibliographic Details
Main Authors: Shayin V. Gibson, Elena Tomas Bort, Lucía Rodríguez-Fernández, Michael D. Allen, Jennifer J. Gomm, Iain Goulding, Ulrich auf dem Keller, Andrea Agnoletto, Cathrin Brisken, Barrie Peck, Angus J. Cameron, John F. Marshall, J. Louise Jones, Edward P. Carter, Richard P. Grose
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-023-00513-6

Internet

https://doi.org/10.1038/s41523-023-00513-6

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