CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies
Abstract Immunotherapy utilizing chimeric antigen receptor T cell (CAR-T) therapy holds promise for hematologic malignancies, however, response rates and associated immune-related adverse effects widely vary among patients. Here we show, by comparing diversity and composition of the gut microbiome d...
Príomhchruthaitheoirí: | , , , , , , , , , , , , , , , , , , |
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Formáid: | Alt |
Teanga: | English |
Foilsithe / Cruthaithe: |
Nature Portfolio
2022-09-01
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Sraith: | Nature Communications |
Rochtain ar líne: | https://doi.org/10.1038/s41467-022-32960-3 |