Dandelion Polysaccharide Exerts Anti-Angiogenesis Effect on Hepatocellular Carcinoma by Regulating VEGF/HIF-1α Expression

Dandelion Polysaccharide Exerts Anti-Angiogenesis Effect on Hepatocellular Carcinoma by Regulating VEGF/HIF-1α Expression

Recent studies have revealed that natural plants-derived polysaccharides exhibit potent anti-tumor activity. Our earlier studies suggest that dandelion polysaccharide (DP) inhibits hepatocellular carcinoma (HCC) cell proliferation in vitro and in vivo. Here, we investigated the effects of DP on the...

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Bibliographic Details
Main Authors: Feng Ren, Kaixuan Wu, Yun Yang, Yingying Yang, Yuxia Wang, Jian Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
hepatocellular carcinoma
dandelion polysaccharide
angiogenesis
vascular endothelial growth factor
hypoxia-inducible factor 1α
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00460/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00460/full

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