A Thermal-Analysis-Technique-Based Mechanistic Approach toward the Release of Omeprazole from Solid Dosage Forms

A Thermal-Analysis-Technique-Based Mechanistic Approach toward the Release of Omeprazole from Solid Dosage Forms

The design, development, and release kinetics of omeprazole (OME) from solid dosage forms have been investigated. These formulations were examined for their resilience in pH = 4.5 buffer solutions and their rate of disintegration in a small-intestine-like environment (pH = 6.8). The results were com...

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Bibliographic Details
Main Authors: Georgios Agapakis, Angeliki Siamidi, Stefanos Kikionis, Marilena Vlachou, Natassa Pippa
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Scientia Pharmaceutica
Subjects:
omeprazole
excipients
thermogravimetric analysis (TGA)
differential scanning calorimetry (DSC)
sustained release
Online Access:https://www.mdpi.com/2218-0532/92/1/8

Internet

https://www.mdpi.com/2218-0532/92/1/8

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