Evaluating E. coli genome‐scale metabolic model accuracy with high‐throughput mutant fitness data

Abstract The Escherichia coli genome‐scale metabolic model (GEM) is an exemplar systems biology model for the simulation of cellular metabolism. Experimental validation of model predictions is essential to pinpoint uncertainty and ensure continued development of accurate models. Here, we quantified...

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Bibliographic Details
Main Authors: David B Bernstein, Batu Akkas, Morgan N Price, Adam P Arkin
Format: Article
Language:English
Published: Springer Nature 2023-12-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.202311566