Plasma and urinary CP I and CP III concentrations in chimeric mice with human hepatocytes after rifampicin administration

Abstract The interest in transporter‐mediated drug interactions has been increasing in the field of drug development. In this study, we measured the plasma and urinary concentrations of coproporphyrin (CP) I and CP III as endogenous substrates for organic anion‐transporting polypeptide (OATP) using...

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Bibliographic Details
Main Authors: Yurina Shishido, Tomohiro Yoshida, Keiyu Oshida, Masashi Uchida
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.70017