Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells

Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells

Abstract Background Senescent cells exert a significant influence over their surrounding cellular environment. Senescent chondrocytes (SnChos) were found to be accumulated in degenerated cartilage present in joints affected by osteoarthritis. The influence of SnChos on exogenously transplanted stem...

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Bibliografische gegevens
Hoofdauteurs: Xu Cao, Pan Luo, Junjie Huang, Chi Liang, Jinshen He, Zili Wang, Dongyong Shan, Cheng Peng, Song Wu
Formaat: Artikel
Taal:English
Gepubliceerd in: BMC 2019-03-01
Reeks:Stem Cell Research & Therapy
Onderwerpen:
Senescent chondrocytes (SnChos)
Bone marrow mesenchymal stem cells (BMSCs)
Intra-articular senescent microenvironment (IASM)
Osteoarthritis (OA)
Cartilage repair
Online toegang:http://link.springer.com/article/10.1186/s13287-019-1193-1

Internet

http://link.springer.com/article/10.1186/s13287-019-1193-1

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