EphA2-specific microvesicles derived from tumor cells facilitate the targeted delivery of chemotherapeutic drugs for osteosarcoma therapy

EphA2-specific microvesicles derived from tumor cells facilitate the targeted delivery of chemotherapeutic drugs for osteosarcoma therapy

Abstract Despite advances in surgery and chemotherapy, the survival of patients with osteosarcoma (OS) has not been fundamentally improved over the last two decades. Microvesicles (MVs) have a high cargo-loading capacity and are emerging as a promising drug delivery nanoplatform. The aim of this stu...

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Bibliographic Details
Main Authors: Zhenggang Wang, Zhiyi He, Junlai Wan, Anmin Chen, Peng Cheng, Wentao Zhu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Nanobiotechnology
Subjects:
EphA2
Osteosarcoma
Nanoplatform
Surface functionalization
Microvesicles
Tumor targeting
Online Access:https://doi.org/10.1186/s12951-024-02372-0

Internet

https://doi.org/10.1186/s12951-024-02372-0

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