Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases

Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases

Steroid hormones synchronize a variety of functions throughout all stages of life. Importantly, steroid hormone-transforming enzymes are ultimately responsible for the regulation of these potent signaling molecules. Germline mutations that cause dysfunction in these enzymes cause a variety of endocr...

Full description

Bibliographic Details
Main Authors: Andrea J. Detlefsen, Ryan D. Paulukinas, Trevor M. Penning
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
aldo-keto reductase
bile acid
deficiency
congenital adrenal hyperplasia
hydroxysteroid dehydrogenase
prostate cancer
Online Access:https://www.mdpi.com/1422-0067/24/3/1873

Internet

https://www.mdpi.com/1422-0067/24/3/1873

Similar Items