The perinucleolar compartment: structure, function, and utility in anti-cancer drug development

ABSTRACTThe perinucleolar compartment (PNC) was initially identified as a nuclear structure enriched for the polypyrimidine tract-binding protein. Since then, the PNC has been implicated in carcinogenesis. The prevalence of this compartment is positively correlated with disease progression in variou...

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Bibliographic Details
Main Authors: Eugene V. Makeyev, Sui Huang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Nucleus
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2024.2306777