The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians.

Understanding the regulatory interactions that control gene expression during the development of novel tissues is a key goal of evolutionary developmental biology. Here, we show that Mbnl3 has undergone a striking process of evolutionary specialization in eutherian mammals resulting in the emergence...

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Bibliographic Details
Main Authors: Thomas Spruce, Mireya Plass, André Gohr, Debashish Ray, María Martínez de Lagrán, Gregor Rot, Ana Nóvoa, Demian Burguera, Jon Permanyer, Marta Miret, Hong Zheng, Maurice S Swanson, Quaid Morris, Moises Mallo, Mara Dierssen, Timothy R Hughes, Barbara Pernaute, Manuel Irimia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001615