Dose-dependent effects of busulfan on dog testes in preparation for spermatogonial stem cell transplantation

Abstract Successful male germ cell transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan, is commonly used for the preparation of recipient models before transplantation, the optimal dos...

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Bibliographic Details
Main Authors: Tai-Young Hur, Seung-Hoon Lee, Sun-A Ock, Hyuk Song, Hyun-Jung Park, Ran Lee, Si-Heung Sung, Hyunjhung Jhun, Won-Young Lee
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Laboratory Animal Research
Subjects:
Online Access:http://link.springer.com/article/10.5625/lar.2017.33.3.264