Dose-dependent effects of busulfan on dog testes in preparation for spermatogonial stem cell transplantation
Abstract Successful male germ cell transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan, is commonly used for the preparation of recipient models before transplantation, the optimal dos...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-12-01
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Series: | Laboratory Animal Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.5625/lar.2017.33.3.264 |