Increased lethality of respiratory infection by Streptococcus pneumoniae in the Dp16 mouse model of Down syndrome
Abstract Objectives We sought to investigate whether the Dp16 mouse model of Down syndrome (DS) is more susceptible to severe and lethal respiratory tract infection by Streptococcus pneumoniae. Study Design We infected controls and Dp16 mice with Streptococcus pneumoniae and measured survival rates....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-12-01
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| Series: | FASEB BioAdvances |
| Online Access: | https://doi.org/10.1096/fba.2023-00091 |