Inverse correlation between promoter strength and excision activity in class 1 integrons.

Class 1 integrons are widespread genetic elements that allow bacteria to capture and express gene cassettes that are usually promoterless. These integrons play a major role in the dissemination of antibiotic resistance among Gram-negative bacteria. They typically consist of a gene (intI) encoding an...

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Bibliographic Details
Main Authors: Thomas Jové, Sandra Da Re, François Denis, Didier Mazel, Marie-Cécile Ploy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2791841?pdf=render