A circuit mechanism for decision-making biases and NMDA receptor hypofunction

A circuit mechanism for decision-making biases and NMDA receptor hypofunction

Decision-making biases can be features of normal behaviour, or deficits underlying neuropsychiatric symptoms. We used behavioural psychophysics, spiking-circuit modelling and pharmacological manipulations to explore decision-making biases during evidence integration. Monkeys showed a pro-variance bi...

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Bibliographic Details
Main Authors: Sean Edward Cavanagh, Norman H Lam, John D Murray, Laurence Tudor Hunt, Steven Wayne Kennerley
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
decision-making
network model
NMDA receptor
schizophrenia
ketamine
Online Access:https://elifesciences.org/articles/53664

Internet

https://elifesciences.org/articles/53664

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