Inferring gene regulatory networks using transcriptional profiles as dynamical attractors.

Genetic regulatory networks (GRNs) regulate the flow of genetic information from the genome to expressed messenger RNAs (mRNAs) and thus are critical to controlling the phenotypic characteristics of cells. Numerous methods exist for profiling mRNA transcript levels and identifying protein-DNA bindin...

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Bibliographic Details
Main Authors: Ruihao Li, Jordan C Rozum, Morgan M Quail, Mohammad N Qasim, Suzanne S Sindi, Clarissa J Nobile, Réka Albert, Aaron D Hernday
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010991