Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival

Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival

Abstract High-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and the majority of cases present with metastasis and late-stage disease. Over the last few decades, the overall survival for patients has not significantly improved, and there are limited targeted treatm...

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Bibliographic Details
Main Authors: Emilee N. Kotnik, Mary M. Mullen, Nicholas C. Spies, Tiandao Li, Matthew Inkman, Jin Zhang, Fernanda Martins-Rodrigues, Ian S. Hagemann, Carolyn K. McCourt, Premal H. Thaker, Andrea R. Hagemann, Matthew A. Powell, David G. Mutch, Dineo Khabele, Gregory D. Longmore, Elaine R. Mardis, Christopher A. Maher, Christopher A. Miller, Katherine C. Fuh
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05026-3

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https://doi.org/10.1038/s42003-023-05026-3

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