Protein kinase C-ε contributes to a chronic inhibitory effect of IL-1β on voltage-gated sodium channels in mice with febrile seizure

This study aimed to understand the role of Interleukin-1β in mouse febrile seizures. To investigate the chronic effects of raised Interleukin-1β on seizures, the sodium currents of hippocampal neurons were recorded by whole-cell voltage clamp. Interleukin-1β inhibited sodium currents in mouse hippoc...

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Bibliographic Details
Main Author: Jinli Wang, Fenfen Xu, Yuan Zheng, Xu Cheng, Piaopiao Zhang, Hongyang Zhao
Format: Article
Language:English
Published: IMR Press 2019-06-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://jin.imrpress.com/fileup/1757-448X/PDF/1563257648503-1039251979.pdf