Virulence-Linked Mutations in Rubredoxin Reductase and Glutaredoxin: Impact on Antibiotic Susceptibility and Phage Therapy in <i>Pseudomonas aeruginosa</i>

Virulence-Linked Mutations in Rubredoxin Reductase and Glutaredoxin: Impact on Antibiotic Susceptibility and Phage Therapy in <i>Pseudomonas aeruginosa</i>

<i>Pseudomonas aeruginosa</i> (PAO1) is an opportunistic pathogen, lethal in immunocompromised individuals. The clinical management of PAO1 infections still depends deeply on antibiotic therapy. However, this therapy has been alarmingly overpowered by growing bacterial resistance mechani...

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Bibliographic Details
Main Authors: Sara Sá, Carina Silva, Maria Clara Dias, Marlene Veiga, Sofia Lopes, Ruben Fernandes, Ana Catarina Rocha, Patrick J. Pais, Marco Oliveira, João Mendes, Gonçalo Novais, Carla Luís, Álvaro Gestoso, José Mário Macedo, Daniela Martins-Mendes, Ana Cláudia Pereira, Pilar Baylina
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Applied Sciences
Subjects:
quorum sensing
oxidative stress
antibiotic stress
biofilm production
virulence
Online Access:https://www.mdpi.com/2076-3417/13/21/11918

Internet

https://www.mdpi.com/2076-3417/13/21/11918

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